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NABP NAPLEX North American Pharmacist Licensure Examination Exam Practice Test

Demo: 23 questions
Total 154 questions

North American Pharmacist Licensure Examination Questions and Answers

Question 1

MT is 47-year-old man who presents to the ER with painful, red, swollen area on his left leg. His temperature is 38.4, respiratory rate 30 and heart rate 95. He has been taking cephalexin day 4 today, as prescribed by his primary care physician. His CMP is normal a CBC shows elevated WBC of 16,000/mm3.

What would be the most appropriate antibiotic/s to initiate on MT empirically?

Options:

A.

Vancomycin IV and Piperacillin/Tazobactam

B.

IV Doxycycline and Ceftazidime

C.

Nafcillin

D.

Vancomycin IV.

E.

Ceftriaxone

Question 2

A CD4 count of 180 cells per cubic meter may be evaluated as which of these?

Options:

A.

Very low

B.

Low

C.

High

D.

Severely high

Question 3

What is the Osmolarity of NS with KCL 40 meq/L? (MW of KCl: 74.55 g/mol) (MW of NaCl: 58.44 g/mol)

Options:

A.

800 mOsm/L

B.

308 mOm/L

C.

1108 mOsm/L

D.

830 mOsm/L

E.

388 mOsm/L

Question 4

You need 51.3 mEq of NaCl to make 1/3 NS 1 liter bag. How many ml of 23.4% NaCl would you need? (Molecular weight of Na is 23 and Cl is 35.5)

Options:

A.

12.82ml B. 16.82ml

B.

23.4ml

C.

58.5ml

D.

10ml

Question 5

An order is received to start Milrinone at 0.75mcg/kg/min, Milrinone comes as 20mg/100ml D5W. What is the infusion rate in mL/hr? Patient weighs 115kg.

Options:

A.

86 mls/hr

B.

13 mls/hr

C.

25.9 mls/hr

D.

43 mls/hr

E.

7 mls/hr

Question 6

A 67-year-old female presents to your clinic complaining of fatigue, diarrhea, headaches and a loss of appetite. Upon examination you find that she is having some cognitive difficulty. Laboratory results reveal: MCV: 109fL; Hgb: 9g/dL; MMA and homocystine are both elevated. Shilling test is positive.

What is the next best step in the management of this patient?

Options:

A.

Lifelong folic acid supplementation

B.

Lifelong Vitamin B12 supplementation

C.

Iron supplementation for 4-6 months

D.

Obtain a Coomb’s test

E.

Give corticosteroids and iron supplementation

Question 7

How many millimoles of sodium are in 0.9% sodium chloride?

Options:

A.

90 millimoles

B.

99 millimoles

C.

145 millimoles

D.

154 millimoles

Question 8

Select the class of Anti-diabetic medication that works in the specified organ to prevent hyperglycemia. Select all that applies. Kidney (G)

Options:

A.

Sulfonylureas

B.

Alpha- Glucosidase Inhibitors

C.

DPP4 Inhibitors

D.

Glucagon-like peptide-1 receptor agonists

E.

Thiazolidinediones

F.

Biguanide

G.

SGLT2 inhibitors

Question 9

Results from a Meta-analysis where they looked at frequency of postoperative arterial fibrillation in patients on Ascorbic acid after cardiac surgery found odds ratio, 0.44 (95% CI, 0.32 to 0.61). How can you interpret this data?

Options:

A.

Ascorbic acid increased frequency of postoperative arterial fibrillation after cardiac surgery by 44%

B.

Ascorbic acid decreased frequency of postoperative arterial fibrillation after cardiac surgery by 44%

C.

There was no statistically significant difference in frequency of postoperative arterial fibrillation after cardiac surgery

D.

Ascorbic acid decreased frequency of postoperative arterial fibrillation after cardiac surgery by 56%

E.

None of the above are correct

Question 10

A 15-year-old presents with 6 days of nasal congestion with thin, clear rhinorrhea. She notes mild facial pain but has had no fevers. She feels her symptoms are improving.

What is the most likely cause of her symptoms?

Options:

A.

Streptococcus pneumoniae

B.

Viral

C.

Moraxella catarrhalis

D.

Haemophilus influenzae

E.

Staphylococcus aureus

Question 11

Which H2-receptor blocker may cause gynecomastia in men due to its antiandrogenic effects?

Options:

A.

Ranitidine

B.

Nizatidine

C.

Cimetidine

D.

Famotidine

Question 12

LT is a 42-year-old white female with past medical history of epilepsy, gastroesophageal reflux disease and seasonal allergies. She weighs 86 kg, height 5’6” and allergic to Aspirin (rash) and Phenobarbital (difficulty breathing).

Her medications include Omeprazole 40mg daily, Phenytoin 200mg twice daily, Valproic acid 500mg four times daily, Loratadine 10mg daily. She comes to your community pharmacy to pick up prescription for Primidone 250mg twice daily.

Pertaining to Primidone what is the most appropriate action to take?

Options:

A.

Notify the physician, Primidone dose is too low.

B.

Notify the physician, Primidone in contraindicated in patient with phenobarbital allergy.

C.

Notify the physician, Primidone in contraindicated in patient with Aspirin allergy.

D.

Notify the physician, patient is already on three anti-seizure medication and primidone is not needed.

E.

Notify the physician, Primidone in contraindicated in patient with gastroesophageal reflux disease.

Question 13

Which of the following antidiabetic medication works by inhibiting carbohydrate breakdown?

Options:

A.

Acarbose

B.

Metformin

C.

Dapagliflozin

D.

Pioglitazone

E.

Sitagliptin

Question 14

If you mix 30 gm 5% lidocaine cream and 90gm of 0.5% hydrocortisone cream, what percent of lidocaine and hydrocortisone do you have as the end product?

Options:

A.

Lidocaine/Hydrocortisone 2%/1.25%

B.

Lidocaine/Hydrocortisone 0.375%/0.15%

C.

Lidocaine/Hydrocortisone 1.25 %/ 0.15%

D.

Lidocaine/Hydrocortisone 2% /0.25%

E.

Lidocaine/Hydrocortisone 1.25% /0.375%

Question 15

Which of the following antidiabetic medication works by decreasing glucose reabsorption?

Options:

A.

Miglitol

B.

Linagliptin

C.

Pioglitazone

D.

Exenatide

E.

Empagliflozin

Question 16

Which of these is an example of postrenal acute kidney injury (AKI)?

Options:

A.

Benign prostatic hyperplasia

B.

Heart failure

C.

Dehydration

D.

Renal vein thrombosis

Question 17

In the US Nurses’ Health Study (NHS) cohort study, where they looked at association of regular aspirin use (≥two 325 mg tablets/week) and colorectal cancer in 82,911 women found (RR, 0.77; 95% CI, 0.67–0.88) over 20 years of follow-up.

In an another analysis of the NHS, regular aspirin use, investigator also found (hazard ratio [HR]=0.72, 95% CI 0.56–0.92), what does this say about the mortality from colorectal cancer? How can this data best be interpreted?

Options:

A.

Those who takes aspirin ≥2 times/week have 23% lower risk of colorectal cancer

B.

Those who takes aspirin ≥2 times/week have 0.77% lower risk of colorectal cancer

C.

Those who takes aspirin ≥2 times/week have 28% lower risk of colorectal cancer

D.

Those who takes aspirin ≥2 times/week have 23% reduction in death from colorectal cancer

E.

None of the above is correct

Question 18

Which of the following beta-blocker is NOT proven to reduce mortality in patients with Systolic CHF?

Options:

A.

Bisoprolol

B.

Nadolol

C.

Carvedilol

D.

Metoprolol succinate

E.

Metoprolol Tartrate

Question 19

Which of the following medication should be avoided if a patient is on lithium to avoid lithium toxicity?

Options:

A.

Lisinopril

B.

Furosemide

C.

Naproxen

D.

Amiodarone

E.

Warfarin

Question 20

A 20-year-old student came to the emergency department with primary complaints of palpitations, low-grade fever, and anxiety for 2 months. She reports that she is irritable and suffers severe mood swings that is interfering with her sleep and relationships (she admits to crying spells and frequent fights with friends and family). She has also lost 12 pounds in the past 2 months with no apparent alteration in her diet or physical activity (though she is happy with her weight loss). She denies any past medical problems, though her friends have always been worried that she eats too little.

Her temperature is 38.0 C (100.4 F), blood pressure is 148/62 mm Hg, pulse is 122/min and regular, and respiratory rate is 28/min. Examination reveals a bruit heard over the anterior neck, fine tremor of the hands, and warm, moist skin. Her eyes and eyelids do not move together during finger following test (with steady head). Laboratory work is sent, including a thyroid panel, but will not be available until tomorrow morning.

Which of the following is the most appropriate initial management at this time?

Options:

A.

Diltiazem therapy

B.

Iodine therapy

C.

Methimazole therapy

D.

Propranolol therapy

E.

Referral to a surgeon

Question 21

A 22-year-old woman adopted a cat. Shortly thereafter, she developed itchy eyes and persistent rhinorrhea. She was clearly allergic to the pet, but desperately wanted to keep it. She tried taking diphenhydramine, but it had intolerable side effects.

Which of the following is a common effect of this type of medication?

Options:

A.

Decreased intraocular pressure

B.

Bradycardia

C.

Xerostomia

D.

Diarrhea

E.

Excessive sweating

Question 22

Diabetic ketoacidosis, a potential complication of type 2 diabetes, is most associated which of the following antidiabetic drug classes?

Options:

A.

DPP-4 inhibitors

B.

SGLT-2 inhibitors

C.

Sulfonylureas

D.

Biguanides

E.

Thiazolidinediones

Question 23

Which of the following side effects should LT be made aware of while on Divalproex Sodium?

Options:

A.

Weight gain

B.

Oligomenorrhea

C.

Alopecia

D.

Gynecomastia

E.

Gingival hyperplasia

Demo: 23 questions
Total 154 questions